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　　三九養(yǎng)生堂記者 鄧肯·蓋伊 報(bào)道

精彩|　　針??(zhen)對(duì)??(dui)這?(zhe)一??(yi)問??(wen)題??(ti)??，該??(gai)研??(yan)究??(jiu)團(tuán)??(tuan)隊(duì)??(dui)研??(yan)發(fā)??(fa)的??(de)CRAQ通??(tong)過??(guo)將??(jiang)原??(yuan)始??(shi)測??(ce)序??(xu)序??(xu)列?(lie)比??(bi)對(duì)??(dui)到?(dao)組??(zu)裝??(zhuang)的?(de)基??(ji)因??(yin)組??(zu)上??(shang)??，基??(ji)于?(yu)序??(xu)列??(lie)比??(bi)對(duì)??(dui)產(chǎn)??(chan)生??(sheng)的??(de)有??(you)效??(xiao)“剪?(jian)切??(qie)對(duì)??(dui)齊??(qi)”信??(xin)息??(xi)??，可??(ke)精??(jing)準(zhǔn)??(zhun)地??(di)檢??(jian)測??(ce)基?(ji)因??(yin)組??(zu)中?(zhong)存??(cun)在??(zai)的??(de)組??(zu)裝??(zhuang)錯(cuò)??(cuo)誤??(wu)??。??結(jié)??(jie)合??(he)長??(chang)讀??(du)長??(chang)測??(ce)序?(xu)片?(pian)段??(duan)和??(he)短??(duan)讀??(du)長??(chang)測??(ce)序??(xu)片??(pian)段??(duan)與??(yu)基??(ji)因??(yin)組??(zu)比??(bi)對(duì)??(dui)的??(de)特??(te)征??(zheng)??，CRAQ可??(ke)以??(yi)識(shí)??(shi)別??(bie)基??(ji)因??(yin)組?(zu)內(nèi)??(nei)小??(xiao)規(guī)??(gui)模??(mo)的??(de)區(qū)??(qu)域?(yu)組??(zu)裝??(zhuang)錯(cuò)??(cuo)誤??(wu)和??(he)大??(da)范??(fan)圍??(wei)的?(de)結(jié)??(jie)構(gòu)??(gou)組??(zu)裝??(zhuang)錯(cuò)??(cuo)誤??(wu)??，不??(bu)同??(tong)類??(lei)別??(bie)的??(de)錯(cuò)??(cuo)誤??(wu)數(shù)??(shu)量??(liang)經(jīng)?(jing)過??(guo)統(tǒng)??(tong)計(jì)??(ji)和??(he)標(biāo)??(biao)準(zhǔn)??(zhun)化??(hua)處??(chu)理??(li)后??(hou)被??(bei)轉(zhuǎn)??(zhuan)化??(hua)為?(wei)兩??(liang)個(gè)??(ge)組??(zu)裝??(zhuang)質(zhì)??(zhi)量?(liang)評(píng)??(ping)估??(gu)指??(zhi)標(biāo)??(biao)??，以??(yi)反??(fan)映??(ying)不??(bu)同??(tong)層??(ceng)面??(mian)的??(de)基??(ji)因??(yin)組??(zu)組??(zu)裝??(zhuang)質(zhì)??(zhi)量??(liang)???！　?jù)?(ju)研??(yan)究??(jiu)團(tuán)??(tuan)隊(duì)??(dui)介??(jie)紹??(shao)??，為??(wei)對(duì)??(dui)CRAQ進(jìn)??(jin)行??(xing)性??(xing)能??(neng)測??(ce)試??(shi)和?(he)評(píng)??(ping)估??(gu)??，他??(ta)們?(men)以?(yi)人??(ren)類??(lei)參??(can)考??(kao)基??(ji)因??(yin)組??(zu)組??(zu)裝??(zhuang)為??(wei)基??(ji)礎(chǔ)??(chu)構(gòu)??(gou)建??(jian)一??(yi)個(gè)??(ge)模??(mo)擬??(ni)數(shù)??(shu)據(jù)??(ju)集??(ji)并??(bing)利??(li)用??(yong)CRAQ和??(he)目??(mu)前??(qian)廣??(guang)泛??(fan)使??(shi)用??(yong)的??(de)基??(ji)因??(yin)組??(zu)質(zhì)??(zhi)量??(liang)評(píng)??(ping)估??(gu)工??(gong)具??(ju)進(jìn)?(jin)行??(xing)測??(ce)試??(shi)和??(he)比?(bi)較??(jiao)??，結(jié)??(jie)果??(guo)表??(biao)明??(ming)??，當(dāng)??(dang)缺??(que)乏??(fa)完??(wan)美??(mei)參??(can)考?(kao)基??(ji)因??(yin)組??(zu)時(shí)??(shi)??，CRAQ表?(biao)現(xiàn)??(xian)最??(zui)佳??(jia)??，并??(bing)在??(zai)檢??(jian)測??(ce)雜??(za)合??(he)區(qū)??(qu)域??(yu)方??(fang)面??(mian)也?(ye)表??(biao)現(xiàn)??(xian)出??(chu)超?(chao)過?(guo)95%的??(de)召??(zhao)回??(hui)率??(lv)和??(he)精??(jing)確??(que)度??(du)?。??研??(yan)究??(jiu)團(tuán)??(tuan)隊(duì)?(dui)還??(hai)通??(tong)過??(guo)對(duì)??(dui)一?(yi)個(gè)??(ge)真??(zhen)實(shí)??(shi)的??(de)果??(guo)蠅??(ying)雜??(za)交??(jiao)的??(de)基??(ji)因??(yin)組??(zu)數(shù)??(shu)據(jù)??(ju)集??(ji)進(jìn)??(jin)行??(xing)分??(fen)析?(xi)??，發(fā)??(fa)現(xiàn)??(xian)CRAQ可??(ke)以??(yi)準(zhǔn)??(zhun)確??(que)地??(di)將??(jiang)組??(zu)裝??(zhuang)錯(cuò)??(cuo)誤??(wu)和??(he)雜??(za)合??(he)區(qū)?(qu)域??(yu)區(qū)?(qu)分??(fen)開??(kai)來?(lai)??，而??(er)其??(qi)他??(ta)工??(gong)具??(ju)則??(ze)無??(wu)法??(fa)檢??(jian)測??(ce)出??(chu)雜??(za)合?(he)區(qū)??(qu)域??(yu)?。(完??(wan))

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