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學(xué)習(xí)快評(píng)丨qibao666888　　當(dāng)??(dang)前??(qian)??，全??(quan)球??(qiu)創(chuàng)??(chuang)新??(xin)藥??(yao)研??(yan)發(fā)??(fa)平??(ping)均??(jun)耗??(hao)時(shí)??(shi)10年?(nian)、耗??(hao)資??(zi)26億??(yi)美??(mei)元??(yuan)??，但??(dan)臨??(lin)床??(chuang)成??(cheng)功??(gong)率??(lv)不??(bu)足??(zu)10%??，其??(qi)原??(yuan)因??(yin)在?(zai)于??(yu)藥??(yao)物??(wu)研??(yan)發(fā)??(fa)過(guò)?(guo)程??(cheng)在??(zai)動(dòng)??(dong)物??(wu)模??(mo)型??(xing)中??(zhong)進(jìn)??(jin)行??(xing)??，不??(bu)能??(neng)模??(mo)擬?(ni)人??(ren)類??(lei)生??(sheng)命??(ming)系?(xi)統(tǒng)??(tong)反??(fan)應(yīng)??(ying)??。??細(xì)??(xi)胞??(bao)譜??(pu)系?(xi)設(shè)??(she)施??(shi)將?(jiang)構(gòu)??(gou)建??(jian)高??(gao)精??(jing)度??(du)單??(dan)細(xì)??(xi)胞??(bao)級(jí)??(ji)別??(bie)數(shù)??(shu)字??(zi)生??(sheng)理??(li)人??(ren)大??(da)模??(mo)型??(xing)??，通??(tong)過(guò)??(guo)回?(hui)溯??(su)、模??(mo)擬??(ni)、預(yù)?(yu)測(cè)?(ce)疾??(ji)病??(bing)細(xì)??(xi)胞??(bao)譜??(pu)系??(xi)演??(yan)化??(hua)??，不??(bu)僅??(jin)可?(ke)以?(yi)精??(jing)準(zhǔn)??(zhun)定??(ding)位?(wei)病??(bing)變??(bian)驅(qū)??(qu)動(dòng)??(dong)關(guān)??(guan)鍵??(jian)靶??(ba)點(diǎn)??(dian)??，還??(hai)可??(ke)以??(yi)用??(yong)數(shù)??(shu)字??(zi)人??(ren)體??(ti)測(cè)??(ce)毒??(du)試??(shi)藥?(yao)??，助??(zhu)力??(li)突??(tu)破??(po)藥??(yao)物??(wu)研??(yan)發(fā)??(fa)瓶?(ping)頸??(jing)??。　　該??(gai)設(shè)??(she)施??(shi)將??(jiang)建?(jian)設(shè)??(she)繪??(hui)制??(zhi)細(xì)??(xi)胞??(bao)譜??(pu)系??(xi)的??(de)自??(zi)動(dòng)??(dong)化??(hua)工??(gong)程??(cheng)產(chǎn)??(chan)線??(xian)??，包??(bao)含??(han)樣?(yang)本??(ben)預(yù)??(yu)處??(chu)理??(li)、樣??(yang)品??(pin)存??(cun)儲(chǔ)??(chu)、多??(duo)尺?(chi)度??(du)成??(cheng)像??(xiang)分??(fen)析??(xi)等??(deng)工?(gong)藝??(yi)流??(liu)程??(cheng)??，標(biāo)??(biao)準(zhǔn)??(zhun)化??(hua)采??(cai)集??(ji)影??(ying)像??(xiang)組??(zu)、空??(kong)間??(jian)組??(zu)、轉(zhuǎn)??(zhuan)錄??(lu)組??(zu)等??(deng)多??(duo)種??(zhong)模??(mo)態(tài)??(tai)數(shù)??(shu)據(jù)??(ju)??，建??(jian)成??(cheng)數(shù)?(shu)字??(zi)孿??(luan)生??(sheng)索??(suo)引??(yin)的??(de)細(xì)??(xi)胞??(bao)譜??(pu)系??(xi)資??(zi)源??(yuan)庫(kù)??(ku)??。?。