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學(xué)習(xí)快評丨qibao666888　　要??(yao)阻??(zu)止??(zhi)這??(zhe)場??(chang)細??(xi)胞??(bao)層??(ceng)面?(mian)的??(de)“暴??(bao)動??(dong)”??，關(guān)??(guan)鍵??(jian)在??(zai)于??(yu)修?(xiu)復(fù)??(fu)失??(shi)靈??(ling)的??(de)“車??(che)速??(su)控??(kong)制??(zhi)”系??(xi)統(tǒng)??(tong)??。??研??(yan)究??(jiu)團??(tuan)隊??(dui)構(gòu)??(gou)建??(jian)了?(le)獨??(du)特??(te)的??(de)藥??(yao)物??(wu)篩??(shai)選??(xuan)平??(ping)臺??(tai)??，用?(yong)熒??(ying)光??(guang)標(biāo)??(biao)記??(ji)細??(xi)胞??(bao)狀??(zhuang)態(tài)??(tai)并??(bing)結(jié)??(jie)合??(he)人??(ren)工??(gong)智??(zhi)能??(neng)分??(fen)析??(xi)??，對??(dui)2404種?(zhong)化??(hua)合??(he)物?(wu)進?(jin)行??(xing)地??(di)毯??(tan)式??(shi)掃??(sao)描??(miao)??。經(jīng)?(jing)過??(guo)多?(duo)輪??(lun)篩??(shai)選??(xuan)??，一??(yi)個??(ge)代??(dai)號??(hao)為??(wei)BMS265246的??(de)小??(xiao)分??(fen)子??(zi)脫??(tuo)穎??(ying)而?(er)出??(chu)???！　《?(ding)勝??(sheng)介??(jie)紹??(shao)說?(shuo)?，這??(zhe)個??(ge)分??(fen)子??(zi)就??(jiu)像??(xiang)一??(yi)把??(ba)特??(te)制??(zhi)的??(de)鑰??(yao)匙??(chi)?，能??(neng)夠??(gou)精??(jing)準(zhǔn)??(zhun)插??(cha)入??(ru)CDK2激??(ji)酶??(mei)的??(de)活??(huo)性??(xing)口??(kou)袋?(dai)??。??這??(zhe)個??(ge)機??(ji)制??(zhi)的??(de)調(diào)??(tiao)控??(kong)不??(bu)像??(xiang)傳??(chuan)統(tǒng)??(tong)抗??(kang)炎?(yan)藥??(yao)那??(na)樣??(yang)全??(quan)面??(mian)壓??(ya)制??(zhi)免??(mian)疫??(yi)系??(xi)統(tǒng)??(tong)?，因??(yin)此??(ci)不??(bu)會??(hui)影??(ying)響??(xiang)其??(qi)他??(ta)正??(zheng)常??(chang)細??(xi)胞?(bao)功??(gong)能??(neng)??。在??(zai)細??(xi)胞??(bao)實??(shi)驗??(yan)中??(zhong)?，BMS265246使??(shi)炎??(yan)癥??(zheng)因??(yin)子??(zi)水??(shui)平??(ping)在??(zai)12小??(xiao)時??(shi)內(nèi)??(nei)恢??(hui)復(fù)?(fu)至??(zhi)正??(zheng)常??(chang)范??(fan)圍??(wei)?，且??(qie)未?(wei)出??(chu)現(xiàn)??(xian)細??(xi)胞??(bao)毒??(du)性??(xing)??。。